葛磊教授

葛磊  教授

 

个人简介

所属学科:应用化学,农药学;研究方向:应用化学、生化分析及生物传感

本人长期从事均相电化学、荧光、光致电化学生物传感、纳米材料的制备与应用等领域的深度研究与开发工作。近几年作为项目主持人承担国家自然科学基金2项、山东省自然科学基金1项。作为第一作者先后在《Advanced Functional Materials》、《Analytical Chemistry》,《Biomaterials》、《ACS Applied Materials & Interfaces》、《Chemical Communications》、《Lab on a chip》、《Analytica Chimica Acta》等期刊上发表SCI收录研究论文25篇。

联系方式:13853283735。电子邮箱:lge#qau.edu.cn

所在课题组主页/channel/lifeng

 

教育及科研经历

2014/07-- 至今     手机网投娱乐大全   分析化学教研室   特聘教授  李峰教授课题组

2011/09--2014/06   山东大学       材料学           博士   导师:程新,合作导师:陶绪堂,于京华

2008/09--2011/06   济南大学       分析化学         硕士   导师:于京华

2004/09--2008/06   济南大学       应用化学         学士

 

第一作者及通讯作者论文

25. Ting Hou, Ningning Xu, Wenxiao Wang, Lei Ge*, Feng Li*, Truly immobilization-free and diffusivity-mediated photoelectrochemical biosensing strategy for facile and highly sensitive microRNA assay, Analytical Chemistry, 2018, 90, 9591–9597.

 

24. Qing Hong, Limin Yang, Lei Ge,* Zhenhui Liu, Feng Li*, Direct-laser-writing of three-dimensional porous graphene frameworks on indium-tin oxide for sensitive electrochemical biosensing, Analyst, 2018, 143, 3327–3334.

 

23. Qing Hong, Lei Ge, Wenxiao Wang, Xiaojuan Liu, Feng LiOligonucleotide-modulated photocurrent enhancement of a tetracationic porphyrin for label-free homogeneous photoelectrochemical biosensing, Biosensors and Bioelectronics, 2018, 121, 90–95.

 

22. Lei Ge, Wenxiao Wang, Feng Li*, Electro-Grafted Electrode with Graphene-Oxide-Like DNA Affinity for Ratiometric Homogeneous Electrochemical Biosensing of MicroRNA, Analytical Chemistry, 2017, 89, 11560−11567.

 

21. Lei Ge*, Ximei Sun, Qing Hong, Feng Li*, Ratiometric Catalyzed-Assembly of NanoCluster Beacons: A Nonenzymatic Approach for Amplified DNA Detection, ACS Applied Materials & Interfaces, 2017, 9, 32089-32096

 

20. Lei Ge, Ximei Sun, Qing Hong, Feng Li*, Ratiometric NanoCluster Beacon: A Label-Free and Sensitive Fluorescent DNA Detection Platform, ACS Applied Materials & Interfaces, 2017, 9, 13102−13110.

 

19. Lei Ge, Wenxiao Wang, Ximei Sun, Ting Hou, Feng Li*, Affinity-Mediated Homogeneous Electrochemical Aptasensor on a Graphene Platform for Ultrasensitive Biomolecule Detection via Exonuclease-Assisted Target-Analog Recycling Amplification, Analytical Chemistry, 2016, 88, 2212–2219.

 

18. Lei Ge, Wenxiao Wang, Ximei Sun, Ting Hou, Feng Li*, Versatile and Programmable DNA Logic Gates on Universal and Label-Free Homogeneous Electrochemical Platform, Analytical Chemistry, 2016, 88, 9691−9698.

 

17. Lei Ge, Wenxiao Wang, Ting Hou, Feng Li*, A versatile immobilization-free photoelectrochemical biosensor for ultrasensitive detection of cancer biomarker based on enzyme-free cascaded quadratic amplification strategy, Biosensors and Bioelectronics, 2016, 77, 220–226.

 

16. Haiyin Li, Jiafu Chang, Ting Hou, Lei Ge*, Feng Li*, A facile, sensitive, and highly specific trinitrophenol assay based on target-induced synergetic effects of acid induction and electron transfer towards DNA-templated copper nanoclusters, Talanta, 2016, 160, 475–480

 

15. Haiyin Li, Chuanfeng Wang, Panpan Gai, Ting Hou, Lei Ge*, Feng Li*, Unique quenching of fluorescent copper nanoclusters based on target-induced oxidation effect: a simple, label-free, highly sensitive and specific bleomycin assay, RSC Advances, 2016, 6, 76679–76683.

 

14. Yaomin Yang, Xiaojuan Liu,* Yingying Lu, Lin Tang, Jinfang Zhang, Lei Ge*, Feng Li*, Visualization of latent fingerprints using a simple "silver imaging ink", Analytical Methods, 2016, 8, 6293–6297.

 

13. Lei Ge, Min Su, Chaomin Gao, Xutang Tao*, Shenguang Ge*, Application of Au cage/Ru(bpy)32+ nanostructures for the electrochemiluminescence detection of K562 cancer cells based on aptamer, Sensors and Actuators B: Chemical, 2015, 214, 144–151.

 

12. Wenxiao Wang#, Lei Ge#, Ximei Sun, Ting Hou, Feng Li*, Graphene-Assisted Label-Free Homogeneous Electrochemical Biosensing Strategy based on Aptamer-Switched Bidirectional DNA Polymerization, ACS Applied Materials & Interfaces, 2015, 7, 28566–28575.

 

11. Lei Ge, Shaowei Wang, Shenguang Ge, Jinghua Yu, Mei Yan*, Nianqiang Li*, Jiadong Huang, Electrophoretic separation in a microfluidic paper-based analytical device with an on-column wireless electrogenerated chemiluminescence detector, Chemical Communications, 2014, 50, 5699–5702.

 

10. Lei Ge, Yanhu Wang, Hongmei Yang, Ping Yang, Xin Cheng, Mei Yan, Jinghua Yu*, A photoelectrochemical biosensor using ruthenium complex-reduced graphene oxide hybrid as the photocurrent signal reporter assembled on rhombic TiO2 nanocrystals driven by visible light, Analytica Chimica Acta, 2014, 828, 27–33.

 

9. Lei Ge, Jinghua Yu*, Shenguang Ge, Mei Yan, Lab-on-paper-based devices using chemiluminescence and electrogenerated chemiluminescence detection, Analytical and Bioanalytical Chemistry, 2014, 406, 5613–5630.

 

8. Lei Ge, Ping Yang, Xin Cheng*, Synthesis of Highly Crystalline Titania Nanocrystals Through Solvothermal Technique, Journal of Nanoscience and Nanotechnology, 2014, 14, 3095–3099.

 

7. Lei Ge, Jinghua Yu*, Drug monitoring: Bright lights yield drug readout, Nature Chemical Biology, 2014, 10, 490–491.

 

6. Lei Ge, Shoumei Wang, Jinghua Yu*, Nianqiang Li, Shenguang Ge, Mei Yan, Molecularly Imprinted Polymer Grafted Porous Au-Paper Electrode for an Microfluidic Electro-Analytical Origami Device, Advanced Functional Materials, 2013, 23, 3115–3123.

 

5. Lei Ge, Panpan Wang, Shenguang Ge, Nianqiang Li, Jinghua Yu*, Mei Yan, Jiadong Huang, Photoelectrochemical lab-on-paper device based on an integrated paper supercapacitor and internal light source, Analytical Chemistry, 2013, 85, 3961–3970.

 

4. Lei Ge, Ning Liu, Ping Yang, Xin Cheng*, Composite TiO2 Film with Quantum Dots Fabricated Through a Sol–Gel Process, Journal of Nanoscience and Nanotechnology, 2013, 13, 2943–2947.

 

3. Lei Ge, Jixian Yan, Xianrang Song, Mei Yan, Shenguang Ge, Jinghua Yu*, Three-dimensional paper-based electrochemiluminescence immunodevice for multiplexed measurement of biomarkers and point-of-care testing, Biomaterials, 2012, 33, 1024–1031.

 

2. Lei Ge, Shoumei Wang, Xianrang Song, Shenguang Ge, Jinghua Yu*, 3D origami-based multifunction-integrated immunodevice: low-cost and multiplexed sandwich chemiluminescence immunoassay on microfluidic paper-based analytical device, Lab on a Chip, 2012, 12, 3150–3158.

 

1. Lei Ge, Ping Dai, Shenguang Ge, Jinghua Yu*, High selectivity chemiluminescence sensor for determination of puerarin in diet foods/weight loss promoters based on novel rhodanine and monodisperse molecularly imprinted microspheres, Analytical Methods, 2010, 2, 1506–1513.

 

第二作者论文

25. Xiaojuan Liu, Lei Ge, Xiuzhong Wang, Wei Li, Feng Li*, Layered double hydroxide functionalized    textile for effective oil/water separation and selective oil adsorption, ACS Applied Materials & Interfaces, 2015, 7, 791–800.

 

24. Min Su, Lei Ge, Qingkun Kong, Xiaoxiao Zheng, Shenguang Ge, Nianqiang Li, Jinghua Yu*, Mei Yan, Cyto-sensing in electrochemical lab-on-paper cyto-device for in-situ evaluation of multi-glycan expressions on cancer cells, Biosensors and Bioelectronics, 2015, 63, 232–239.

 

23. Xiuzhong Wang, Lei Ge, Yanfei Yu, Shanshan Dong, Feng Li*, Highly sensitive electrogenerated chemiluminescence biosensor based on hybridization chain reaction and amplification of gold nanoparticles for DNA detection, Sensors and Actuators B: Chemical, 2015, 220, 942–948.

 

22. Yanhu Wang, Lei Ge, Chao Ma, Qingkun Kong, Mei Yan, Shenguang Ge, Jinghua Yu*, Self-powered and sensitive DNA detection in a three-dimensional origami-based biofuel cell based on a porous Pt-paper cathode, Chemistry–A European Journal, 2014, 20, 12453–12462.

 

21. Yanhu Wang, Lei Ge, Panpan Wang, Mei Yan, Jinghua Yu*, Shenguang Ge, A three-dimensional origami-based immuno-biofuel cell for self-powered, low-cost, and sensitive point-of-care testing, Chemical Communications, 2014, 50, 1947–1949.

 

20. Yan Zhang, Lei Ge, Meng Li, Mei Yan, Shenguang Ge, Jinghua Yu*, Xianrang Song, Bingqiang Cao, Flexible paper-based ZnO nanorod light-emitting diodes induced multiplexed photoelectrochemical immunoassay, Chemical Communications, 2014, 50, 1417–1419.

 

19. Min Su, Lei Ge, Shenguang Ge, Nianqiang Li, Jinghua Yu*, Mei Yan, Jiadong Huang, Paper-based electrochemical cyto-device for sensitive detection of cancer cells and in situ anticancer drug screening, Analytica Chimica Acta, 2014, 847, 1–9.

 

18. Panpan Wang, Lei Ge, Shenguang Ge, Jinghua Yu*, Mei Yan, Jiadong Huang, A paper-based photoelectrochemical immunoassay for low-cost and multiplexed point-of-care testing, Chemical Communications, 2013, 49, 3294–3296.

 

17. Yanhu Wang, Lei Ge, Panpan Wang, Mei Yan, Shenguang Ge, Nianqiang Li, Jinghua Yu*, Jiadong Huang, Photoelectrochemical lab-on-paper device equipped with a porous Au-paper electrode and fluidic delay-switch for sensitive detection of DNA hybridization, Lab on a Chip, 2013, 13, 3945–3955.

 

16. Meng Zhang, Lei Ge, Shenguang Ge, Mei Yan, Jinghua Yu*, Jiadong Huang, Su Liu, Three-dimensional paper-based electrochemiluminescence device for simultaneous detection of Pb2+ and Hg2+ based on potential-control technique, Biosensors and Bioelectronics, 2013, 41, 544–550.

 

15. Shoumei Wang, Lei Ge, Long Li, Mei Yan, Shenguang Ge, Jinghua Yu*, Molecularly imprinted polymer grafted paper-based multi-disk micro-disk plate for chemiluminescence detection of pesticide, Biosensors and Bioelectronics, 2013, 50, 262–268.

 

14. Shenguang Ge, Lei Ge, Mei Yan, Xianrang Song, Jinghua Yu*, Shanshan Liu, A disposable immunosensor device for point-of-care test of tumor marker based on copper-mediated amplification, Biosensors and Bioelectronics, 2013, 43, 425–431.

 

13. Mei Yan, Lei Ge, Weiqiang Gao, Jinghua Yu,* Xianrang Song, Shenguang Ge, Zhiyong Jia, Chengchao Chu, Electrogenerated Chemiluminescence from a Phenyleneethynylene Derivative and its Ultrasensitive Immunosensing Application Using a Nanotubular Mesoporous Pt–Ag Alloy for Signal Amplification, Advanced Functional Materials, 2012, 22, 3899–3906.

 

12. Shaowei Wang, Lei Ge, Yan Zhang, Xianrang Song, Nianqiang Li, Shenguang Ge, Jinghua Yu*, Battery-triggered microfluidic paper-based multiplex electrochemiluminescence immunodevice based on potential-resolution strategy, Lab on a Chip, 2012, 12, 4489–4498.

 

11. Jixian Yan, Lei Ge, Xianrang Song, Mei Yan, Shenguang Ge, Jinghua Yu*, Paper-based electrochemiluminescent 3D immunodevice for lab-on-paper, specific, and sensitive point-of-care testing, Chemistry-A European Journal, 2012, 18, 4938–4945.

 

10. Shenguang Ge, Lei Ge, Mei Yan, Xianrang Song, Jinghua Yu*, Jiadong Huang, A disposable paper-based electrochemical sensor with an addressable electrode array for cancer screening, Chemical Communications, 2012, 48, 9397–9399.

 

9. Dejin Zang, Lei Ge, Mei Yan, Xianrang Song, Jinghua Yu*, Electrochemical immunoassay on a 3D microfluidic paper-based device, Chemical Communications, 2012, 48, 4683–4685.

 

8. Shoumei Wang, Lei Ge, Xianrang Song, Jinghua Yu*, Shenguang Ge, Jiadong Huang, Fang Zeng, Paper-based chemiluminescence ELISA: lab-on-paper based on chitosan modified paper device and wax-screen-printing, Biosensors and Bioelectronics, 2012, 31, 212–218.

 

7. Panpan Wang, Lei Ge, Mei Yan, Xianrang Song, Shenguang Ge, Jinghua Yu*, Paper-based three-dimensional electrochemical immunodevice based on multi-walled carbon nanotubes functionalized paper for sensitive point-of-care testing, Biosensors and Bioelectronics, 2012, 32, 238–243.

 

6. Shoumei Wang, Lei Ge, Xianrang Song, Mei Yan, Shenguang Ge, Jinghua Yu*, Fang Zeng, Simple and covalent fabrication of a paper device and its application in sensitive chemiluminescence immunoassay, Analyst, 2012, 137, 3821–3827.

 

5. Jinghua Yu*, Lei Ge, Jiadong Huang, Shoumei Wang, Shenguang Ge, Microfluidic paper-based chemiluminescence biosensor for simultaneous determination of glucose and uric acid, Lab on a Chip, 2011, 11, 1286–1291.

 

4. Jinghua Yu*, Lei Ge, Shiquan Liu, Ping Dai, Shenguang Ge, Wei Zheng, Facile and scalable synthesis of a novel rigid artificial superoxide dismutase based on modified hollow mesoporous silica microspheres, Biosensors and Bioelectronics, 2011, 26, 1936–1941.

 

3. Jinghua Yu*, Lei Ge, Ping Dai, Shenguang Ge, Shiquan Liu, A novel enzyme biosensor for glucose based on rhodanine derivative chemiluminescence system and mesoporous hollow silica microspheres receptor, Biosensors and Bioelectronics, 2010, 25, 2065–2070.

 

2. Jinghua Yu*, Lei Ge, Ping Dai, Congcong Zhang, Shenguang Ge, Jiadong Huang, A novel glucose chemiluminescence biosensor based on a rhodanine derivative chemiluminescence system and multilayer-enzyme membrane, Turkish Journal Of Chemistry, 2010, 34, 489–498.

 

1. Jinghua Yu, Lei Ge, Ping Dai, Congcong Zhang, Shenguang Ge, Jiadong Huang*, Highly selective determination of phenolphthalein by flow injection chemiluminescence method based on a molecular imprinting polymer, Luminescence, 2009, 24, 444–447.

 

在研项目

国家自然科学基金应急管理项目(21545005),主持

国家自然科学基金青年科学基金项目(31501570),主持

山东省自然科学基金青年科学基金项目(ZR2014BQ011),主持

青岛市自主创新计划(应用基础研究) (16-5-1-55-jch),主持

 

授权专利

葛磊,王文晓,孙锡梅,侯婷,李峰,一种免固定生物传感电极的制备及其在免标记均相光致电化学农残检测与癌症诊断中的应用,授权号:ZL 201510734897.5